Isocyanide chemistry enabled by continuous flow technology

Enabled by the continuous advancement in fabrication technology, present day synchronous microprocessors include more than 100

Enabled by the continuous advancement in fabrication technology, present day synchronous microprocessors include more than 100 million transistors and have clock speeds well in excess of the 1GHz mark. Distributing a low-skew clock signal in this frequency range to all areas of a large chip is a task of growing complexity. As a solution to this problem, designers have recently suggested the use...

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Application of magnetohydrodynamic actuation to continuous flow chemistry.

Continuous flow microreactors with an annular microchannel for cyclical chemical reactions were fabricated by either bulk micromachining in silicon or by rapid prototyping using EPON SU-8. Fluid propulsion in these unusual microchannels was achieved using AC magnetohydrodynamic (MHD) actuation. This integrated micropumping mechanism obviates the use of moving parts by acting locally on the elec...

3D-printed devices for continuous-flow organic chemistry

We present a study in which the versatility of 3D-printing is combined with the processing advantages of flow chemistry for the synthesis of organic compounds. Robust and inexpensive 3D-printed reactionware devices are easily connected using standard fittings resulting in complex, custom-made flow systems, including multiple reactors in a series with in-line, real-time analysis using an ATR-IR ...

Flow Chemistry – A Key Enabling Technology for (Multistep) Organic Synthesis

Laboratory scaled flow-through processes have seen an explosive development over the past decade and have become an enabling technology for improving synthetic efficiency through automation and process optimization. Practically, flow devices are a crucial link between bench chemists and process engineers. The present review focuses on two unique aspects of modern flow chemistry where substantia...